Residual respiratory impairment after COVID-19 pneumonia

نویسندگان

چکیده

Abstract Introduction The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing potential for long-term sequelae in these patients. We assessed function cohort patients after recovering infection, stratified according PaO 2 /FiO (p/F) values. Method Approximately one month hospital discharge, 86 COVID-19 underwent physical examination, arterial blood gas (ABG) analysis, pulmonary tests (PFTs), six-minute walk test (6MWT). Patients were also asked quantify severity dyspnoea cough before, during, hospitalization using visual analogic scale (VAS). Seventy-six subjects with ABG during three groups their worst p/F values: above 300 (n = 38), between 200 30) below 20). Results On PFTs, lung volumes overall preserved yet, mean percent predicted residual volume was slightly reduced (74.8 ± 18.1%). Percent diffusing capacity carbon monoxide (DLCO) mildly (77.2 16.5%). reported breathlessness at time visit (VAS 19.8, p < 0.001). had lower forced vital (p 0.005), total 0.012), DLCO 0.001) shorter 6MWT distance 0.004) than higher p/F. Conclusion have impairment, including exercise tolerance. extent this impairment seems correlate failure hospitalization.

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ژورنال

عنوان ژورنال: BMC Pulmonary Medicine

سال: 2021

ISSN: ['1471-2466']

DOI: https://doi.org/10.1186/s12890-021-01594-4